Natamycin (INN), also known as pimaricin, is a naturally occurring antimicrobial agent produced by the bacterium Streptomyces natalensis.
Natamycin lacks acute toxicity. In animal studies, the lowest LD50 found was 450 mg/kg. In rats, the LD50 is ¡Ý2300 mg/kg, and doses of 500 mg/kg/day over 2 years caused no ***ectable differences in survival rate, growth, or incidence of tumors. The metabolites of natamycin also lack toxicity. The breakdown products of natamycin under various storage conditions may have a lower LD50 than natamycin, but in all cases the numbers are quite high. In humans, a dose of 500 mg/kg/day repeated over multiple days caused nausea, vomiting, and diarrhea.
You can contact us if you want to order this product. |
Home
